PRF therapy

The dental medicine and maxillofacial surgery ward of Medicus Alpha is the only where the team is experienced in PRF-therapy in oral surgery. PRF is the acronym for Platelet Rich Fibrin bioproduct. It contains a fibrin matrix polymerized in a tetramolecular structure. Incorporated in it are platelets, leukocytes, cytokines, and circulating stem cells that build all other cells in the human body. Platelets regulate several important functions in the body, including the coagulation and the production of the growth factor, which is in charge of the wound healing. The growth factor stimulates the stem cells to form new tissue as fast as possible, and this is the reason why PRF is so important and efficient in the recovery period following an invasive treatment. Medicus Alpha Clinic has extensive experience in applying this innovative technology in dental medicine, oral and maxillofacial surgery. Here are the several ways PRF is used in clinical dentistry:

 

  • Improvement and acceleration of the process of osteoformation in maxillofacial surgery implanting
  • Sinuses surgery
  • Restoration of facial bones
  • Restoration of the jaw bones after removal of cysts
  • Restoration of gingival changes (receding gums) – periodontal surgeries
  • Resolving bone loss in patients treated for cancer metastases in other body parts, as with bisphosphonate-related osteonecrosis seen in cancer patients.
  • Treatment of sinus perforation and fistula located within mouth and the maxillary sinuses.


The application of PRF is gaining growing popularity in various restorative processes, too. Among the major advantages of the PRF-therapy are:

  • Faster healing – when the wound get saturated with PRF, the regenerative abilities of the tissue, due to the growth factor contained in the PRF, abruptly increase. This quicker regeneration, on its turn lowers the risk of infection, complications at a later stage, and discomfort.
  • Safety – the method is completely safe, since PRF practically is a product obtained individually for each particular patient from their own blood. The quantity of blood is not large and drawing it bears no risk for the patient either.
  • Low infection risk – during procedure, the wound is dressed with PRF, thus practically it is sealed against the infection agents and therefore the risk of inflammation considerably decreases.

How is individual PRF derived for each particular patient?
Immediately before the beginning of therapy, the necessary quantity of blood (about 60 ml) is being drawn from the patient. The blood is processed in a special centrifuge, separating the blood plasma and fibrine form the red blood cells. Afterward, employing a special technology, a fibirne auto-implant rich in growth factor is derived from the plasma. Usually PRF is applied immediately after stitching the wound to the entire area of surgical operation, accelerating by many times the healing process and considerably decreasing discomfort.